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Dr Eman Ali Ali Aboul Gasim

Job: Lecturer in Pharmacology

Faculty: Health and Life Sciences

School/department: Leicester School of Pharmacy

Address: Â鶹ƵµÀ, The Gateway, Leicester, LE1 9BH

T: +44 (0) 116 250 8117

E: ealial00@dmu.ac.uk

 

Personal profile

Eman worked on using cellular assays to study the immune response of different
potential vaccine candidates for schistosomiasis, a neglected tropical disease using a Leukaemia cell (RS-ATL-8). She started working as a research fellow in Prof. Chris Denning’s lab in 2017. The project was focused on the use of hiPSC derived cardiomyocytes in the phenotype evaluation of myotonic dystrophy (DM1) and discovering the molecular therapeutics that can shift the phenotype toward the normal. She also worked as a postdoctoral researcher in gene therapy using Mesenchymal Stem Cells (Immortalised and primary cell line), at the School of Pharmacy, Nottingham.

Research group affiliations

Leicester Institute of Pharmaceutical Innovation for Integrated Care (LIPIIC)

Publications and outputs

  • 2014: Use of Humanised Rat Basophilic Leukaemia Cell Line RSATL8 for the Assessment of Allergenicity of Schistosoma mansoni Proteins, PLoS Negl Trop Dis. Daniel Wan, Fernanda Ludolf, Daniel G. W. Alanine, Owen Stretton ,Eman Ali Ali , Nafal Al-Barwary1 , Xiaowei Wang, Michael J. Doenhoff , Adriano Mari, Colin M. Fitzsimmons , David W. Dunne , Ryosuke Nakamura , Guilherme C.Oliveira , Marcos J. C. Alcocer , Franco H. Falcone
  • 2017: Use of humanized RS-ATL8 reporter system for detection of allergen-specific IgE sensitization in human food allergy, Volume 1592 of the series Methods in Molecular Biology pp147-161, 2017. Eman Ali Ali, Ryosuke Nakamura and Franco H. Falcone
  • 2019: Characterization of human FcεRIα chain expression and gene copy number in humanized rat basophilic leukaemia (RBL) reporter cell lines SX-38, RS-ATL8, RBL-703/21 and NFAT-DsRed. s. PLoS ONE 14(8): e0221034 Eman Ali Ali, Marina Kalli, Daniel Wan, Xiaowei Wang, Ryosuke Nakamura, David Onion, Daniel G. W. Alanine, Marcos J. C. Alcocer and Franco H. Falcone
  • 2019: Deep molecular phenotyping of myotonic dystrophy (DM1) hiPSC-cardiomyocytes to facilitate risk stratification and drug evaluation (In prep) Eman Ali Ali, Spandan Karla, Sarah Cumming, Darren Monkton David Brook and Chris Denning

Research interests/expertise

Regenerative Medicine, Stem Cell Biology, Molecular Therapeutics

Areas of teaching

Pharmacology

Qualifications

2013-2017 Ph.D in Pharmacy, Molecular Therapeutics and Formulation, University of Nottingham
2012-2013 MRes in Pharmacy, Molecular Therapeutics and Formulation, University of Nottingham
2010-2012 MSc in Pharmacology (Clinical Pharmacokinetics Specialisation), UMST, Sudan
2005-2010 BSc in Pharmacy, UMST, Sudan

Honours and awards

2016: Gordon Memorial College Trust Fund, UK 
2015: Gordon Memorial College Trust Fund, UK 
2015: Graduate School Travel Prize, University of Nottingham
2014: Gordon Memorial College Trust Fund, UK 
2013: Vice Chancellor’s scholarship for Research Excellence, University of Nottingham 
2012: Developing Solutions master scholarship, University of Nottingham 
2010: BSc in Pharmacy, First class honour.